HepCBC.bull April 1998

 

To INF or not to INF: Part Two

(The following interchange between Perry the Winkle and Tim Halloran was posted to the HEPV-L list and is part of a broader discussion)

On Friday, 13 March, 1998, Perry the Winkle posted: "My quality of life is a lot better than many of the reports I've read here [on the list], and I've never taken Interferon."

Tim: "This is to be expected in a lot of cases. Remember, Hep C is 'The Silent Epidemic'. The reason a lot of people don't know they have it is that they don't have symptoms so they don't get tested for the disease."

Perry: "Still, I function at a fairly high level. The normal brain fog, depression, aches, pains, and fatigue and so on commonly associated with this bug (on or off Interferon and other drugs) has been very much reduced."

Tim: "Here too, taking care of yourself, eating a low-fat diet, doing moderate exercise, getting plenty of rest, and taking herbal supplements can greatly reduce symptoms. But symptoms can come and go with no apparent connection to how well you are taking care of yourself."

Perry: "I may eventually develop (or even be developing) cirrhosis, or cancer."

Tim: "Maybe yes, maybe no. I felt 'just fine' for years--never having any real symptoms except a little fatigue now and then when I pushed myself too hard. My liver enzymes were 'slightly elevated'. I took care of myself, got a flu shot every year, ate a low-fat diet, etc., etc. - but still my liver deteriorated. A few years ago I found myself gaining weight, having a lot edema, getting muscle cramps, needing more sleep. During a laparoscopic gall bladder removal in 1996, surgeons took photos of my liver and suggested that I start thinking about a liver transplant as my liver was close to 90% cirrhotic. Later that year I was hospitalised for endocarditis, at which time my liver doc visited me in the hospital and said that it was time to get screened for a transplant. The infection that caused the endocarditis and the heavy-duty antibiotics were taking their toll and I should now consider myself to suffer from 'end-stage' liver disease. I was transplanted on June 6, 1997. The post surgical analysis of my diseased liver showed two tiny hepatocellular carcinomas. I had been transplanted just in the nick of time."

Perry: "To get that result, I take herbs. My liver enzymes went down, but not the PCR..The herbs are based on a traditional Chinese liver formulas."

Tim: "Here is where I must take issue with you. There are no controls over the growing, drying and packaging of Chinese herbs. Particularly in the drying process there is ample cause for concern. The herbs are dried in the open air, and it is not unusual for the herbs to be rained upon then allowed to re-dry in the sun. The problem is that moulds can develop on the plants. Also, livestock can contaminate adjacent soil by eliminating waste. Then too, there is no standardisation by which anyone can determine to any degree of accuracy how much of the active ingredient of the herb one is getting. Those herbs may actually be doing something good for you until the day you take some that are contaminated. Then your already-compromised liver is really in trouble. Then there is the problem that there has been no scientifically-sound research (i.e., double blind and/or linear studies) to prove the efficacy of these herbs. The Milk Thistle and St. John's Wort you take may actually be doing more for you than your Chinese herbs. There are a number of European studies that link Milk Thistle to reduced liver enzymes and link St. John's Wort to alleviating depression. Common sense mineral supplements may also play a major role in alleviating the symptoms of Hep C. I took Milk Thistle for years. Although it did help to keep my enzymes only 'slightly-elevated', it didn't stop the progression of the disease. Elevated enzymes are an indication of ongoing insult to the liver. I wouldn,t pass on interferon or interferon/ribavirin just because it has a mediocre success rate. It might work for you. You COULD become PCR negative and have your liver enzymes return to normal, MAYBE. I would think it was worth the try. The alternative is to do nothing and definitely progress to cirrhosis, liver cancer, and end-stage liver disease."

"Any day above ground is a good one" Tim Halloran, The Bear.

Table of Contents

Therapeutic Touch:
Reach Out and Dupe Someone?

by Linda Rosa

ACSH Volume 8 Number 3 1996

Nurses do some strange things for their patients. They hang crystals on IV poles, necklace their patients with herbs and channel astral entities. But the strangest nursing practice of all - and the most widespread - may be Therapeutic Touch (TT). Every day nurses enter hospital rooms across the U.S. to perform this ritual, which they claim heals their patients. TT is often performed without the knowledge of the physician in charge and usually without the patient's informed consent.

TT was developed at New York University's school of nursing by Dolores Krieger, Ph.D., R.N., who first described it in a 1975 American Journal of Nursing article claiming that TT could increase blood levels of the oxygen-carrying molecule hemoglobin. Krieger says that TT is the healing transfer of prana, an ayurvedic or Hindu concept of "life force." Others say it resembles qi, the mystical root of Chinese folk medicine. You'd assume from its name that TT relies on the palliative effects of human contact. But actually, it doesn't involve any touching at all. In TT, a nurse, sometimes called a healer, waves her hands two to six inches over the patient's body, working from head to toe. Her hands interact with a supposed "human energy field" that surrounds the body. After she detects "differences" in the field indicating disease or trauma, her waving hands then smooth or "unruffle" the patient's energy aura, relieving discomfort and allowing the body to heal itself.

TT is premised on the notion that there really are human energy fields that TT can modify. But when the University of Colorado, a major center of TT activism, empanelled a blue-ribbon jury to review the science behind TT, the jury could find no evidence for such fields.

Although TT practitioners [admit] that the existence and nature of the energy field is a hypothesis which has not been confirmed in over 20 years, in practice they behave as if the energy field were a perceptible reality. There is virtually no acceptable scientific evidence concerning the existence or nature of these energy fields. There is no ongoing research on this concept. . . nor are there any plans for such research, nor even any ideas about how such research might be conducted.

TT's proponents dismiss such criticisms as scientific nitpicking. "[Having] a Ph.D. in physics is not necessary to understand new theories and the meaning they may have for nursing practice," says nursing professor Therese C. Meehan. For her and others, it's enough that they have seen TT work; whether it has a scientific basis is irrelevant.

TT researchers have made numerous claims for what the technique can do. Among the supposed benefits:

  • TT accelerates the healing process in 99.5 percent of cases. The rate at which new bone forms during the healing of fractures, for example, is more than doubled when TT is used.
  • TT strengthens the immune systems of both practitioners and recipients.
  • TT stimulates the circulatory and lymphatic systems.
  • TT relieves the side effects of AIDS, Alzheimer's disease and thyroid imbalances.
  • TT can improve the prognosis for many different types of cancer.

The studies claiming therapeutic benefits from TT have serious flaws, however:

  • All of them lack a suitable placebo group.
  • The numbers of patients in the studies are too small for the findings to be statistically valid.
  • Hardly any of the studies that show benefits from TT have been conducted "double blind." (In double-blind studies, neither the patients nor those judging the outcome know who receives treatment and who doesn't).
  • When well-done studies involving TT-treated patients and a placebo group have been conducted, they have failed to find any therapeutic benefit from TT.
  • Studies showing that TT helps patients have not been replicated.

Quoting again from the Colorado panel's report: "To date [1994] there is not a sufficient body of data, both in quality and quantity, to establish TT as a unique and efficacious healing modality. There are major gaps in the literature regarding the actual efficacy of the practice of non-contact TT as a unique healing modality."

But, its proponents ask, "Even if scientific support is lacking, what's the harm in doing TT?" The answer, of course, is that harm can occur in many ways: when patients neglect effective treatments in favor of ineffective ones; when false hopes and expectations are raised; and when insurance, hospital, and out-of-pocket costs are incurred and no benefit results.

Despite the lack of evidence that TT works, use of the technique is increasing. TT has now become entrenched in the nursing profession and is actually accepted as a standard treatment.

According to its advocates, TT is taught in at least 80 nursing schools, with some schools even giving graduate credit for it. The National League for Nursing, the accrediting agency for curricula in nursing schools, has long promoted TT through books and tapes. Most states allow nurses to maintain their licenses by taking continuing-education courses in TT. Staff nurses from Michigan to Hawaii have been called on the carpet in their hospitals for refusing to practice TT.

Why has nursing embraced TT?

It helps raise the stature of the profession in the eyes of patients and nurses as well. A nurse administering TT becomes a healer on a par with a doctor. In addition, TT helps augment nurses' incomes. Nurses opening private practices commonly charge $35 for a 20-minute TT session.

Unfortunately, nursing has no equivalent to medicine's or dentistry's Councils of Scientific Affairs, which assess the safety, efficacy and appropriateness of unregulated procedures. So there is no way for the profession to formulate a policy against the practice of TT.

Can the government do anything about an unproven practice that has gained legitimacy?

If TT's practitioners waved a wand instead of their hands - particularly a wand connected to a box with some knobs and dials - then the Food and Drug Administration (FDA) could regulate TT as a medical device, and the burden would be on its advocates to prove that it works. But TT involves no devices and, in any event, federal authorites have no direct control over professional practice.

The federal government has actually been supporting TT rather than deterring it. Recently, Congress mandated that the National Institutes of Health set up an "Office of Alternative Medicine" (OAM), which has given for researching the usefulness of TT in treating stress. The Department of Defense, meanwhile, has given $355,000 to a University of Alabama team looking at TT's ability to reduce pain and infection in burn patients.

Most nurses who practice TT genuinely believe that it helps patients. But patients should not infer from a nurse's sincerity or professional credentials that TT is a valid treatment. In fact, despite TT's widespread use, there is no evidence that it provides any benefit whatever.

Linda Rosa , R.N., is a writer in Loveland, CO, and chair of the Questionable Nurse Practices Task Force of The National Council Against Health Fraud.

©1997 & 1998 American Council on Science and Health

Table of Contents

Adverse Events Associated with Interferon Alfa Therapy in Patients with Chronic HCV

Rakesh Vinayek, A. Obaid Shakil

Interferons are proteins with antiviral, antiproliferative and immunomodulatory activities. Interferon alfa has been used extensively for the treatment of patients with chronic viral hepatitis. Virtually all patients treated with interferon alfa develop adverse effects, most of which are transient and subside spontaneously. Among the more serious side-effects, neuropsychiatric are the commonest, and include marked somnolence, depression, psychosis, suicidal ideation and seizures. Ocular disorders such as retinal hemorrhages and exudates occur frequently, particularly in patients with diabetes mellitus and hypertension. Autoimmune disorders, such as thyroiditis, develop in a significant proportion of patients treated. Interferon alfa can also exacerbate pre-existent autoimmune diseases, such as rheumatoid arthritis and diabetes mellitus. It often causes mild myelosuppression which may result in leukopenia, thrombocytopenia or anemia. Other disorders reported to occur include, severe hepatic dysfunction, gastrointestinal disturbance, interstitial pneumonitis and various skin conditions. Patients on interferon alfa, especially those with decompensated cirrhosis, are more prone to develop serious, often life-threatening infections. Thus, adverse events in most patients treated with interferon alfa are mild and reversible; however, serious problems can develop. Patients and their families should therefore be fully informed, regarding the risks involved, prior to institution of interferon alfa therapy.

© 1997 W.B. Saunders Company Ltd

Keywords:

interferon alfa; adverse events; chronic hepatitis

Source:

http://www.hbuk.co.uk/hb/journals/vh/vh97/vh003.003/vh970034.art/0034h.htm

Viral Hepatitis Reviews Abstract Volume 3 Number 3, September 1997, p 167= -177

Table of Contents


This page hosted by Get your ownFree Home Page